Acelofenac

NSAID Pain Reliever | Anti-inflammatory Medication

⚠ī¸ Important Safety Information

Always consult with a healthcare professional before starting any medication. This information is for educational purposes only and should not replace professional medical advice.

What is Acelofenac?

Acelofenac is a commonly used anti-inflammatory drug. It is more or less similar to diclofenac. It is a excellent painkiller in the class of non-steroidal anti-inflammatory drugs (NSAIDs). Acelofenac is used to reduce pain in conditions like osteoarthritis, rheumatoid arthritis, shoulder pain, neck pain, back pain, migraines, post-cataract surgery, dysmenorrhea (painful periods), sprains, and spasms

📌 Uses

Acelofenac is commonly used to treat:

  • Pain relief in short term
  • Inflammation
  • Reduces swelling of joints and muscles

Dosage

  • Adults: 500 MG Tablet of acelofenac can be taken orally every 4 to 6 hours. You should be careful about total dose you are taking per day, it should not exceed beyond 4 GM (heavy alcohol users should not exceed dose beyond 2 GM per day)
  • Children: acelofenac is unsafe to use in children. Any dose is avoided

⚠ī¸ Side Effects

  • Nausea
  • Vomiting
  • Skin rash
  • Constipation

🔍 Precautions

Before taking Acelofenac, tell your doctor if you have:

  • 🍷 Alcohol: Heavy alcohol consumptions increases the risk of liver injury. Dosage in such people should be guided by physician.
  • 🤰 Pregnancy: It is advised to consult physician before taking Acelofenac tablet.
  • 🤱 Breastfeeding: Acelofenac is safe to use in lactating mothers. Human studies have shown that very small amount of drug is passed in breastmilk and is not harmful to the baby
  • 🚗 Driving: Acelofenac tablet does not affect while you are driving
  • LiverLiver: Acelofenac tablet should be used with caution in liver disease. Certainly, dose adjustment is needed. Please consult your doctor. In active liver disease it is not advisable to consume Acelofenac.
  • KidneyKidney: Acelofenac tablet should be used with caution in kidney disease. Dose adjustment will be beneficial. Please consult your doctor. However, Acelofenac is considered safest painkiller for patients with kidney disease

🔄 Drug Interactions

  • With Alcohol- consuming alcohol with Acelofenac increase the risk of stomach bleeding.
  • With Methotrexate - increases methotrexate toxicity by reducing its renal elimination.
  • With Digoxin - increases blood Digoxin levels by reducing renal clearance. It causes Digoxin toxicity.
  • With lithium - increases blood lithium levels by reducing renal clearance. It causes lithium toxicity.
  • With anti-hypertensive drugs like ACE inhibitors , beta blockers, diuretics - reduces efficacy of this blood pressure lowering drugs by inhibiting renal prostaglandin synthesis and reduced renal perfusion.

    • đŸ“Ļ Storage

    • Store at room temperature (68-77°F or 20-25°C)
    • Keep in original container, tightly closed
    • Protect from moisture and light
    • Keep out of reach of children
    • Do not use if tablets smell like vinegar (sign of breakdown)

    💡 Quick tips from experts:

    • Take with food or milk to reduce gastric upset.
    • Take it as per doctors prescription. Dont increase the dose and duration of treatment.
    • Long term use of diclofenac can cause stomach bleeding and kidney problems.
    • It may cause drowsiness or visual disturbances. Take precaution if you are working in industry with heavy machineries, driving or doing anything that requires attention.
    • Stay away from alcohol while you are consuming diclofenac.
    • You should inform your doctor if you have a history of heart conditions or stroke.
    • Your physician may monitor your liver enzymes and kidney function ,if you are taking this drug for long-term treatment.

    ℹī¸ Facts about Acelofenac:

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    • Chemical name: Phenylacetic derivative
    • Class of drug: pain analgesics
    • Habit forming: NO
    • Action starts within: 30-60 min

    🚨 Emergency Information

    In case of overdose, contact poison control immediately at 1-800-222-1222 or seek emergency medical attention. Symptoms of overdose may include severe nausea, vomiting, stomach pain, confusion, ringing in ears, fever, and difficulty breathing.

    📚 Resources

    • 1] Brunton LL, Knollmann BC, editors. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 14th ed. New York: McGraw-Hill Education; 2023.
    • 2] Katzung BG, Vanderah TW. Basic & Clinical Pharmacology. 16th ed. New York: McGraw-Hill; 2024.